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Massive Depletion of Bovine Leukemia Virus Proviral Clones Located in Genomic Transcriptionally Active Sites during Primary Infection

Deltaretroviruses such as human T-lymphotropic virus type 1 (HTLV-1) and bovine leukemia virus (BLV) induce a persistent infection that remains generally asymptomatic but can also lead to leukemia or lymphoma. These viruses replicate by infecting new lymphocytes (i.e. the infectious cycle) or via cl...

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Detalles Bibliográficos
Autores principales: Gillet, Nicolas A., Gutiérrez, Gerónimo, Rodriguez, Sabrina M., de Brogniez, Alix, Renotte, Nathalie, Alvarez, Irene, Trono, Karina, Willems, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789779/
https://www.ncbi.nlm.nih.gov/pubmed/24098130
http://dx.doi.org/10.1371/journal.ppat.1003687