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Multiple Signaling Pathways Coordinate to Induce a Threshold Response in a Chordate Embryo
In animal development, secreted signaling molecules evoke all-or-none threshold responses of target gene transcription to specify cell fates. In the chordate Ciona intestinalis, the neural markers Otx and Nodal are induced at early embryonic stages by Fgf9/16/20 signaling. Here we show that three ad...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789818/ https://www.ncbi.nlm.nih.gov/pubmed/24098142 http://dx.doi.org/10.1371/journal.pgen.1003818 |