Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway

Macroautophagy is a conserved mechanism for the bulk degradation of proteins and organelles. Pathological studies have implicated defective macroautophagy in neurodegeneration, but physiological functions of macroautophagy in adult neurons remain unclear. Here we show that Atg7, an essential macroau...

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Detalles Bibliográficos
Autores principales: Inoue, Keiichi, Rispoli, Joanne, Yang, Lichuan, MacLeod, David, Beal, M. Flint, Klann, Eric, Abeliovich, Asa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789823/
https://www.ncbi.nlm.nih.gov/pubmed/24098148
http://dx.doi.org/10.1371/journal.pgen.1003845

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