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Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle

Binding of the macrophage lectin mincle to trehalose dimycolate, a key glycolipid virulence factor on the surface of Mycobacterium tuberculosis and Mycobacterium bovis, initiates responses that can lead both to toxicity and to protection of these pathogens from destruction. Crystallographic structur...

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Detalles Bibliográficos
Autores principales:	Feinberg, Hadar, Jégouzo, Sabine A. F., Rowntree, Thomas J. W., Guan, Yue, Brash, Matthew A., Taylor, Maureen E., Weis, William I., Drickamer, Kurt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789947/ https://www.ncbi.nlm.nih.gov/pubmed/23960080 http://dx.doi.org/10.1074/jbc.M113.497149

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