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Heterochromatic Gene Silencing by Activator Interference and a Transcription Elongation Barrier

Heterochromatin silences transcription, contributing to development, differentiation, and genome stability in eukaryotic organisms. Budding yeast heterochromatic silencing is strictly dependent on the silent information regulator (SIR) complex composed of the Sir2 histone deacetylase and the chromat...

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Detalles Bibliográficos
Autores principales:	Johnson, Aaron, Wu, Ronghu, Peetz, Matthew, Gygi, Steven P., Moazed, Danesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Gene Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789973/ https://www.ncbi.nlm.nih.gov/pubmed/23940036 http://dx.doi.org/10.1074/jbc.M113.460071

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