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N-(4-Acetyl-3-methyl-1-phenyl-1H-pyrazol-5-yl)-N-methyl-2-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)benzamide

In the title compound, C(29)H(25)N(5)O(3), the dihedral angle between the benzene ring and the pendant quinazoline ring system (r.m.s. deviation = 0.036Å) is 87.60 (17)°. The equivalent angle between the pyrazole ring and the phenyl group is 70.0 (2)°. The dihedral angle between the benzene and pyra...

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Detalles Bibliográficos
Autores principales: Meneghetti, Fiorella, Maggio, Benedetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790439/
https://www.ncbi.nlm.nih.gov/pubmed/24098258
http://dx.doi.org/10.1107/S1600536813025683
Descripción
Sumario:In the title compound, C(29)H(25)N(5)O(3), the dihedral angle between the benzene ring and the pendant quinazoline ring system (r.m.s. deviation = 0.036Å) is 87.60 (17)°. The equivalent angle between the pyrazole ring and the phenyl group is 70.0 (2)°. The dihedral angle between the benzene and pyrazole rings is 30.7 (2)° and overall, the mol­ecular conformation approximates to a Z shape. A short intra­molecular C—H⋯O contact occurs. In the crystal, the mol­ecules are linked by Cπ—H⋯O-type hydrogen bonds and aromatic π–π stacking inter­actions [centroid–centroid distance = 3.860 (3) Å], generating a three-dimensional network.