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New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells

sp(2)-Iminosugar-type castanospermine analogues have been shown to exhibit anti-tumor activity. However, their effects on cell proliferation and apoptosis and the molecular mechanism at play are not fully understood. Here, we investigated the effect of two representatives, namely the pseudo-S- and C...

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Detalles Bibliográficos
Autores principales: Allan, Ghada, Ouadid-Ahidouch, Halima, Sanchez-Fernandez, Elena M., Risquez-Cuadro, Rocío, Fernandez, José M. Garcia, Ortiz-Mellet, Carmen, Ahidouch, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790671/
https://www.ncbi.nlm.nih.gov/pubmed/24124558
http://dx.doi.org/10.1371/journal.pone.0076411