Nuclear Factor κ-B Is Activated in the Pulmonary Vessels of Patients with End-Stage Idiopathic Pulmonary Arterial Hypertension

OBJECTIVES: To assess activation of the inflammatory transcription factor NF-kappa B (NF-κB) in human idiopathic pulmonary arterial hypertension (PAH). BACKGROUND: Idiopathic PAH is a severe progressive disease characterized by pulmonary vascular remodeling and excessive proliferation of vascular ce...

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Detalles Bibliográficos
Autores principales: Price, Laura C., Caramori, Gaetano, Perros, Frederic, Meng, Chao, Gambaryan, Natalia, Dorfmuller, Peter, Montani, David, Casolari, Paolo, Zhu, Jie, Dimopoulos, Konstantinos, Shao, Dongmin, Girerd, Barbara, Mumby, Sharon, Proudfoot, Alastair, Griffiths, Mark, Papi, Alberto, Humbert, Marc, Adcock, Ian M., Wort, S. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790752/
https://www.ncbi.nlm.nih.gov/pubmed/24124488
http://dx.doi.org/10.1371/journal.pone.0075415

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