Optimization and Pharmacological Validation of a Leukocyte Migration Assay in Zebrafish Larvae for the Rapid In Vivo Bioactivity Analysis of Anti-Inflammatory Secondary Metabolites

Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug discovery. In this study, we explore the suitability of zebrafish larvae to rapidly evaluate the anti-inflammatory activity of natural products (NPs) and medicinal plants used in traditional medicine f...

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Detalles Bibliográficos
Autores principales: Cordero-Maldonado, María Lorena, Siverio-Mota, Dany, Vicet-Muro, Liliana, Wilches-Arizábala, Isabel María, Esguerra, Camila V., de Witte, Peter A. M., Crawford, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790782/
https://www.ncbi.nlm.nih.gov/pubmed/24124487
http://dx.doi.org/10.1371/journal.pone.0075404

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