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Targeting and Cytotoxicity of SapC-DOPS Nanovesicles in Pancreatic Cancer
Only a small number of promising drugs target pancreatic cancer, which is the fourth leading cause of cancer deaths with a 5-year survival of less than 5%. Our goal is to develop a new biotherapeutic agent in which a lysosomal protein (saposin C, SapC) and a phospholipid (dioleoylphosphatidylserine,...
Autores principales: | Chu, Zhengtao, Abu-Baker, Shadi, Palascak, Mary B., Ahmad, Syed A., Franco, Robert S., Qi, Xiaoyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790873/ https://www.ncbi.nlm.nih.gov/pubmed/24124494 http://dx.doi.org/10.1371/journal.pone.0075507 |
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