HER-2 gene amplification in human breast cancer without concurrent HER-2 over-expression

BACKGROUND: Testing for human epidermal growth factor receptor-2 (HER-2) in breast cancer is performed by either immunohistochemistry (IHC) or in situ hybridization (ISH). The growth factor receptor-bound protein-7 (GRB7) gene is in close proximity to HER-2 on chromosome 17q11-12 and codes a signal...

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Detalles Bibliográficos
Autores principales: Luoh, Shiuh-Wen, Ramsey, Betsy, Hanlon Newell, Amy, Troxell, Megan, Hu, Zhi, Chin, Koei, Spellman, Paul, Olson, Susan, Keenan, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791222/
https://www.ncbi.nlm.nih.gov/pubmed/24102037
http://dx.doi.org/10.1186/2193-1801-2-386

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