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Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment()

The aim of the present study was to investigate the role of beta oscillatory responses upon cognitive load in healthy subjects and in subjects with mild cognitive impairment (MCI). The role of beta oscillations upon cognitive stimulation is least studied in comparison to other frequency bands. The s...

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Autores principales: Güntekin, Bahar, Emek-Savaş, Derya Durusu, Kurt, Pınar, Yener, Görsev Gülmen, Başar, Erol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791295/
https://www.ncbi.nlm.nih.gov/pubmed/24179847
http://dx.doi.org/10.1016/j.nicl.2013.07.003
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author Güntekin, Bahar
Emek-Savaş, Derya Durusu
Kurt, Pınar
Yener, Görsev Gülmen
Başar, Erol
author_facet Güntekin, Bahar
Emek-Savaş, Derya Durusu
Kurt, Pınar
Yener, Görsev Gülmen
Başar, Erol
author_sort Güntekin, Bahar
collection PubMed
description The aim of the present study was to investigate the role of beta oscillatory responses upon cognitive load in healthy subjects and in subjects with mild cognitive impairment (MCI). The role of beta oscillations upon cognitive stimulation is least studied in comparison to other frequency bands. The study included 17 consecutive patients with MCI (mean age = 70.8 ± 5.6 years) according to Petersen's criteria, and 17 age- and education-matched normal elderly controls (mean age = 68.5 ± 5.5 years). The experiments used a visual oddball paradigm. EEG was recorded at 30 cortical locations. EEG-evoked power, inter-trial phase synchronization, and event-related beta responses filtered in 15–20 Hz were obtained in response to target and non-target stimuli for both groups of subjects. In healthy subjects, EEG-evoked beta power, inter-trial phase synchronization of beta responses and event-related filtered beta responses were significantly higher in responses to target than non-target stimuli (p < 0.05). In MCI patients, there were no differences in evoked beta power between target and non-target stimuli. Furthermore, upon presentation of visual oddball paradigm, occipital electrodes depict higher beta response in comparison to other electrode sites. The increased beta response upon presentation of target stimuli in healthy subjects implies that beta oscillations could shift the system to an attention state, and had important function in cognitive activity. This may, in future, open the way to consider beta activity as an important operator in brain cognitive processes.
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spelling pubmed-37912952013-10-31 Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment() Güntekin, Bahar Emek-Savaş, Derya Durusu Kurt, Pınar Yener, Görsev Gülmen Başar, Erol Neuroimage Clin Article The aim of the present study was to investigate the role of beta oscillatory responses upon cognitive load in healthy subjects and in subjects with mild cognitive impairment (MCI). The role of beta oscillations upon cognitive stimulation is least studied in comparison to other frequency bands. The study included 17 consecutive patients with MCI (mean age = 70.8 ± 5.6 years) according to Petersen's criteria, and 17 age- and education-matched normal elderly controls (mean age = 68.5 ± 5.5 years). The experiments used a visual oddball paradigm. EEG was recorded at 30 cortical locations. EEG-evoked power, inter-trial phase synchronization, and event-related beta responses filtered in 15–20 Hz were obtained in response to target and non-target stimuli for both groups of subjects. In healthy subjects, EEG-evoked beta power, inter-trial phase synchronization of beta responses and event-related filtered beta responses were significantly higher in responses to target than non-target stimuli (p < 0.05). In MCI patients, there were no differences in evoked beta power between target and non-target stimuli. Furthermore, upon presentation of visual oddball paradigm, occipital electrodes depict higher beta response in comparison to other electrode sites. The increased beta response upon presentation of target stimuli in healthy subjects implies that beta oscillations could shift the system to an attention state, and had important function in cognitive activity. This may, in future, open the way to consider beta activity as an important operator in brain cognitive processes. Elsevier 2013-07-17 /pmc/articles/PMC3791295/ /pubmed/24179847 http://dx.doi.org/10.1016/j.nicl.2013.07.003 Text en © 2013 The Authors http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Güntekin, Bahar
Emek-Savaş, Derya Durusu
Kurt, Pınar
Yener, Görsev Gülmen
Başar, Erol
Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment()
title Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment()
title_full Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment()
title_fullStr Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment()
title_full_unstemmed Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment()
title_short Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment()
title_sort beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791295/
https://www.ncbi.nlm.nih.gov/pubmed/24179847
http://dx.doi.org/10.1016/j.nicl.2013.07.003
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