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Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor

Self-renewal of pluripotent mouse embryonic stem (ES) cells is sustained by the cytokine leukaemia inhibitory factor (LIF) acting through the transcription factor Stat3. Several targets of Stat3 have previously been identified, most notably the reprogramming factor Klf4. However, such factors are ne...

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Detalles Bibliográficos
Autores principales: Martello, Graziano, Bertone, Paul, Smith, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791366/
https://www.ncbi.nlm.nih.gov/pubmed/23942233
http://dx.doi.org/10.1038/emboj.2013.177