Cargando…
The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study
Objectives. To investigate associations between muscle strength and pain sensitivity among healthy volunteers and associations between different pain sensitivity measures. Methods. Twenty-eight healthy volunteers (21 females) participated. Pressure pain thresholds (PPTs) were obtained from 1) comput...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791575/ https://www.ncbi.nlm.nih.gov/pubmed/24167727 http://dx.doi.org/10.1155/2013/787054 |
_version_ | 1782286741618556928 |
---|---|
author | Henriksen, Marius Klokker, Louise Bartholdy, Cecilie Graven-Nielsen, Thomas Bliddal, Henning |
author_facet | Henriksen, Marius Klokker, Louise Bartholdy, Cecilie Graven-Nielsen, Thomas Bliddal, Henning |
author_sort | Henriksen, Marius |
collection | PubMed |
description | Objectives. To investigate associations between muscle strength and pain sensitivity among healthy volunteers and associations between different pain sensitivity measures. Methods. Twenty-eight healthy volunteers (21 females) participated. Pressure pain thresholds (PPTs) were obtained from 1) computer-controlled pressure algometry on the vastus lateralis and deltoid muscles and on the infrapatellar fat pad and 2) computerized cuff pressure algometry applied on the lower leg. Deep-tissue pain sensitivity (intensity and duration) was assessed by hypertonic saline injections into the vastus lateralis, deltoid, and infrapatellar fat pad. Quadriceps and hamstring muscle strength was assessed isometrically at 60-degree knee flexion using a dynamometer. Associations between pain sensitivity and muscle strength were investigated using multiple regressions including age, gender, and body mass index as covariates. Results. Knee extension strength was associated with computer-controlled PPT on the vastus lateralis muscle. Computer-controlled PPTs were significantly correlated between sites (r > 0.72) and with cuff PPT (r > 0.4). Saline induced pain intensity and duration were correlated between sites (r > 0.39) and with all PPTs (r < −0.41). Conclusions. Pressure pain thresholds at the vastus lateralis are positively associated with knee extensor muscle strength. Different pain sensitivity assessment methods are generally correlated. The cuff PPT and evoked infrapatellar pain seem to reflect the general pain sensitivity. This trial is registered with ClinicalTrials.gov: NCT01351558. |
format | Online Article Text |
id | pubmed-3791575 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37915752013-10-28 The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study Henriksen, Marius Klokker, Louise Bartholdy, Cecilie Graven-Nielsen, Thomas Bliddal, Henning Pain Res Treat Research Article Objectives. To investigate associations between muscle strength and pain sensitivity among healthy volunteers and associations between different pain sensitivity measures. Methods. Twenty-eight healthy volunteers (21 females) participated. Pressure pain thresholds (PPTs) were obtained from 1) computer-controlled pressure algometry on the vastus lateralis and deltoid muscles and on the infrapatellar fat pad and 2) computerized cuff pressure algometry applied on the lower leg. Deep-tissue pain sensitivity (intensity and duration) was assessed by hypertonic saline injections into the vastus lateralis, deltoid, and infrapatellar fat pad. Quadriceps and hamstring muscle strength was assessed isometrically at 60-degree knee flexion using a dynamometer. Associations between pain sensitivity and muscle strength were investigated using multiple regressions including age, gender, and body mass index as covariates. Results. Knee extension strength was associated with computer-controlled PPT on the vastus lateralis muscle. Computer-controlled PPTs were significantly correlated between sites (r > 0.72) and with cuff PPT (r > 0.4). Saline induced pain intensity and duration were correlated between sites (r > 0.39) and with all PPTs (r < −0.41). Conclusions. Pressure pain thresholds at the vastus lateralis are positively associated with knee extensor muscle strength. Different pain sensitivity assessment methods are generally correlated. The cuff PPT and evoked infrapatellar pain seem to reflect the general pain sensitivity. This trial is registered with ClinicalTrials.gov: NCT01351558. Hindawi Publishing Corporation 2013 2013-09-17 /pmc/articles/PMC3791575/ /pubmed/24167727 http://dx.doi.org/10.1155/2013/787054 Text en Copyright © 2013 Marius Henriksen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Henriksen, Marius Klokker, Louise Bartholdy, Cecilie Graven-Nielsen, Thomas Bliddal, Henning The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study |
title | The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study |
title_full | The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study |
title_fullStr | The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study |
title_full_unstemmed | The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study |
title_short | The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study |
title_sort | associations between pain sensitivity and knee muscle strength in healthy volunteers: a cross-sectional study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791575/ https://www.ncbi.nlm.nih.gov/pubmed/24167727 http://dx.doi.org/10.1155/2013/787054 |
work_keys_str_mv | AT henriksenmarius theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT klokkerlouise theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT bartholdycecilie theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT gravennielsenthomas theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT bliddalhenning theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT henriksenmarius associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT klokkerlouise associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT bartholdycecilie associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT gravennielsenthomas associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy AT bliddalhenning associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy |