Cargando…

The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study

Objectives. To investigate associations between muscle strength and pain sensitivity among healthy volunteers and associations between different pain sensitivity measures. Methods. Twenty-eight healthy volunteers (21 females) participated. Pressure pain thresholds (PPTs) were obtained from 1) comput...

Descripción completa

Detalles Bibliográficos
Autores principales: Henriksen, Marius, Klokker, Louise, Bartholdy, Cecilie, Graven-Nielsen, Thomas, Bliddal, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791575/
https://www.ncbi.nlm.nih.gov/pubmed/24167727
http://dx.doi.org/10.1155/2013/787054
_version_ 1782286741618556928
author Henriksen, Marius
Klokker, Louise
Bartholdy, Cecilie
Graven-Nielsen, Thomas
Bliddal, Henning
author_facet Henriksen, Marius
Klokker, Louise
Bartholdy, Cecilie
Graven-Nielsen, Thomas
Bliddal, Henning
author_sort Henriksen, Marius
collection PubMed
description Objectives. To investigate associations between muscle strength and pain sensitivity among healthy volunteers and associations between different pain sensitivity measures. Methods. Twenty-eight healthy volunteers (21 females) participated. Pressure pain thresholds (PPTs) were obtained from 1) computer-controlled pressure algometry on the vastus lateralis and deltoid muscles and on the infrapatellar fat pad and 2) computerized cuff pressure algometry applied on the lower leg. Deep-tissue pain sensitivity (intensity and duration) was assessed by hypertonic saline injections into the vastus lateralis, deltoid, and infrapatellar fat pad. Quadriceps and hamstring muscle strength was assessed isometrically at 60-degree knee flexion using a dynamometer. Associations between pain sensitivity and muscle strength were investigated using multiple regressions including age, gender, and body mass index as covariates. Results. Knee extension strength was associated with computer-controlled PPT on the vastus lateralis muscle. Computer-controlled PPTs were significantly correlated between sites (r > 0.72) and with cuff PPT (r > 0.4). Saline induced pain intensity and duration were correlated between sites (r > 0.39) and with all PPTs (r < −0.41). Conclusions. Pressure pain thresholds at the vastus lateralis are positively associated with knee extensor muscle strength. Different pain sensitivity assessment methods are generally correlated. The cuff PPT and evoked infrapatellar pain seem to reflect the general pain sensitivity. This trial is registered with ClinicalTrials.gov: NCT01351558.
format Online
Article
Text
id pubmed-3791575
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-37915752013-10-28 The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study Henriksen, Marius Klokker, Louise Bartholdy, Cecilie Graven-Nielsen, Thomas Bliddal, Henning Pain Res Treat Research Article Objectives. To investigate associations between muscle strength and pain sensitivity among healthy volunteers and associations between different pain sensitivity measures. Methods. Twenty-eight healthy volunteers (21 females) participated. Pressure pain thresholds (PPTs) were obtained from 1) computer-controlled pressure algometry on the vastus lateralis and deltoid muscles and on the infrapatellar fat pad and 2) computerized cuff pressure algometry applied on the lower leg. Deep-tissue pain sensitivity (intensity and duration) was assessed by hypertonic saline injections into the vastus lateralis, deltoid, and infrapatellar fat pad. Quadriceps and hamstring muscle strength was assessed isometrically at 60-degree knee flexion using a dynamometer. Associations between pain sensitivity and muscle strength were investigated using multiple regressions including age, gender, and body mass index as covariates. Results. Knee extension strength was associated with computer-controlled PPT on the vastus lateralis muscle. Computer-controlled PPTs were significantly correlated between sites (r > 0.72) and with cuff PPT (r > 0.4). Saline induced pain intensity and duration were correlated between sites (r > 0.39) and with all PPTs (r < −0.41). Conclusions. Pressure pain thresholds at the vastus lateralis are positively associated with knee extensor muscle strength. Different pain sensitivity assessment methods are generally correlated. The cuff PPT and evoked infrapatellar pain seem to reflect the general pain sensitivity. This trial is registered with ClinicalTrials.gov: NCT01351558. Hindawi Publishing Corporation 2013 2013-09-17 /pmc/articles/PMC3791575/ /pubmed/24167727 http://dx.doi.org/10.1155/2013/787054 Text en Copyright © 2013 Marius Henriksen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Henriksen, Marius
Klokker, Louise
Bartholdy, Cecilie
Graven-Nielsen, Thomas
Bliddal, Henning
The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study
title The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study
title_full The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study
title_fullStr The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study
title_full_unstemmed The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study
title_short The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study
title_sort associations between pain sensitivity and knee muscle strength in healthy volunteers: a cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791575/
https://www.ncbi.nlm.nih.gov/pubmed/24167727
http://dx.doi.org/10.1155/2013/787054
work_keys_str_mv AT henriksenmarius theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT klokkerlouise theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT bartholdycecilie theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT gravennielsenthomas theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT bliddalhenning theassociationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT henriksenmarius associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT klokkerlouise associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT bartholdycecilie associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT gravennielsenthomas associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy
AT bliddalhenning associationsbetweenpainsensitivityandkneemusclestrengthinhealthyvolunteersacrosssectionalstudy