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Lack of correlation between in silico projection of function and quantitative real-time PCR-determined gene expression levels in colon tissue

There are a number of in silico programs that use algorithms and external web sources to predict the effect of single nucleotide polymorphisms (SNPs). While many of these programs have been shown to predict accurately the effect of SNPs in functional areas of the gene, such as 5′ upstream or coding...

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Detalles Bibliográficos
Autores principales: Penney, Rosalind B, Lundgreen, Abbie, Yao-Borengasser, Aiwei, Koroth-Edavana, Vineetha, Williams, Suzanne, Wolff, Roger, Slattery, Martha L, Kadlubar, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791675/
https://www.ncbi.nlm.nih.gov/pubmed/24101876
http://dx.doi.org/10.2147/PGPM.S49199

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