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Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase

Most currently available small molecule inhibitors of DNA replication lack enzymatic specificity, resulting in deleterious side effects during use in cancer chemotherapy and limited experimental usefulness as mechanistic tools to study DNA replication. Towards development of targeted replication inh...

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Detalles Bibliográficos
Autores principales:	Simon, Nicholas, Bochman, Matthew L., Seguin, Sandlin, Brodsky, Jeffrey L., Seibel, William L., Schwacha, Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2013
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791872/ https://www.ncbi.nlm.nih.gov/pubmed/24001138 http://dx.doi.org/10.1042/BSR20130083

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