Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug

Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, cha...

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Detalles Bibliográficos
Autores principales: Garaga, Srinivas, Raghava Reddy, Ambati V., Prabahar, Koilpillai Joseph, Korupolu, Raghu Babu, Sanasi, Paul Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791930/
https://www.ncbi.nlm.nih.gov/pubmed/24106664
http://dx.doi.org/10.3797/scipharm.1212-21
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author Garaga, Srinivas
Raghava Reddy, Ambati V.
Prabahar, Koilpillai Joseph
Korupolu, Raghu Babu
Sanasi, Paul Douglas
author_facet Garaga, Srinivas
Raghava Reddy, Ambati V.
Prabahar, Koilpillai Joseph
Korupolu, Raghu Babu
Sanasi, Paul Douglas
author_sort Garaga, Srinivas
collection PubMed
description Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, characterization, and control of these dimers along with the synthesis of Despropylene Gatifloxacin (metabolite).
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spelling pubmed-37919302013-10-08 Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug Garaga, Srinivas Raghava Reddy, Ambati V. Prabahar, Koilpillai Joseph Korupolu, Raghu Babu Sanasi, Paul Douglas Sci Pharm Research Article Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, characterization, and control of these dimers along with the synthesis of Despropylene Gatifloxacin (metabolite). Österreichische Apotheker-Verlagsgesellschaft 2013 2013-02-18 /pmc/articles/PMC3791930/ /pubmed/24106664 http://dx.doi.org/10.3797/scipharm.1212-21 Text en © Garaga et al.; licensee Österreichische Apotheker-Verlagsgesellschaft m. b. H., Vienna, Austria. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Garaga, Srinivas
Raghava Reddy, Ambati V.
Prabahar, Koilpillai Joseph
Korupolu, Raghu Babu
Sanasi, Paul Douglas
Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug
title Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug
title_full Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug
title_fullStr Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug
title_full_unstemmed Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug
title_short Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug
title_sort synthesis and characterization of potential dimers of gatifloxacin – an antibacterial drug
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791930/
https://www.ncbi.nlm.nih.gov/pubmed/24106664
http://dx.doi.org/10.3797/scipharm.1212-21
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