Cargando…

Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug

Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, cha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garaga, Srinivas, Raghava Reddy, Ambati V., Prabahar, Koilpillai Joseph, Korupolu, Raghu Babu, Sanasi, Paul Douglas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791930/ https://www.ncbi.nlm.nih.gov/pubmed/24106664 http://dx.doi.org/10.3797/scipharm.1212-21

Ejemplares similares

Synthesis and Characterization of Impurities in the Production Process of Lopinavir
por: Raghava Reddy, Ambati V., et al.
Publicado: (2015)

Synthesis and Characterization of Compounds Related to Lisinopril
por: Raghava Reddy, Ambati V., et al.
Publicado: (2016)

Synthesis of Isomeric and Potent Impurities of the Triazole-Based Antifungal Drug Voriconazole
por: Sundaram, Dhanraj T. S. S., et al.
Publicado: (2015)

A Facile, Improved Synthesis of Sildenafil and Its Analogues
por: Raghava Reddy, Ambati. V., et al.
Publicado: (2015)

An Alternative Approach to Isoganciclovir: A Prominent Impurity in the Antiviral Drug Ganciclovir
por: Sundaram, Dhanraj T. S. S., et al.
Publicado: (2015)

Preparation and in vitro antibacterial evaluation of gatifloxacin mucoadhesive gellan system
por: Kesavan, K., et al.
Publicado: (2010)

Synthesis of compounds related to the anti-migraine drug eletriptan hydrobromide
por: Madasu, Suri Babu, et al.
Publicado: (2012)

Sodium Alginate Based Mucoadhesive System for Gatifloxacin and Its In Vitro Antibacterial Activity
por: Kesavan, Karthikeyan, et al.
Publicado: (2010)

Design of a Controlled-Release Delivery Composite of Antibacterial Agent Gatifloxacin by Spherical Silica Nanocarrier
por: Guo, Xueping, et al.
Publicado: (2022)

Efficacy of Gatifloxacin in Acute Bacterial Corneal ulcer
por: Afzal Junejo, Sameen, et al.
Publicado: (2013)

Comparison of Drug Concentrations in Human Aqueous Humor after the Administration of 0.3% Gatifloxacin Ophthalmic Gel, 0.3% Gatifloxacin and 0.5% Levofloxacin Ophthalmic Solutions
por: Ding, Wenting, et al.
Publicado: (2015)

Ultrasound-assisted gatifloxacin delivery in mouse cornea, in vivo
por: Jegal, Uk, et al.
Publicado: (2019)

Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis
por: Cervantes, Lorenzo J, et al.
Publicado: (2011)

Intraocular penetration of sequentially instilled topical moxifloxacin, gatifloxacin, and levofloxacin
por: Sugioka, Koji, et al.
Publicado: (2009)

Ocular insert for sustained delivery of gatifloxacin sesquihydrate: Preparation and evaluations
por: Khurana, Gaurav, et al.
Publicado: (2012)

Gatifloxacin Loaded Nano Lipid Carriers for the Management of Bacterial Conjunctivitis
por: Joshi, Poorva H., et al.
Publicado: (2023)

A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis
por: Li, Mengna, et al.
Publicado: (2022)

Conformational adaptability determining antibody recognition to distomer: structure analysis of enantioselective antibody against chiral drug gatifloxacin
por: Wang, Lanteng, et al.
Publicado: (2021)

An Open Randomized Comparison of Gatifloxacin versus Cefixime for the Treatment of Uncomplicated Enteric Fever
por: Pandit, Anil, et al.
Publicado: (2007)

Concentrations of besifloxacin, gatifloxacin, and moxifloxacin in human conjunctiva after topical ocular administration
por: Torkildsen, Gail, et al.
Publicado: (2010)

Effect of gatifloxacin against Mycoplasma genitalium-related urethritis: an open clinical trial
por: Hamasuna, Ryoichi, et al.
Publicado: (2011)

Gatifloxacin Ophthalmic Solution for Treatment of Bacterial Conjunctivitis: Safety, Efficacy and Patient Perspective
por: Schultz, Clyde
Publicado: (2012)

Bilayered Films Based on Novel Polymer Derivative for Improved Ocular Therapy of Gatifloxacin
por: Aher, Naval Dinesh, et al.
Publicado: (2014)

Surface-modified gatifloxacin nanoparticles with potential for treating central nervous system tuberculosis
por: Marcianes, Patricia, et al.
Publicado: (2017)

Gatifloxacin versus chloramphenicol for uncomplicated enteric fever: an open-label, randomised, controlled trial
por: Arjyal, Amit, et al.
Publicado: (2011)

Moxifloxacin and gatifloxacin for initial therapy of tuberculosis: a meta-analysis of randomized clinical trials
por: Ruan, Qiaoling, et al.
Publicado: (2016)

Preparation and characterization of gatifloxacin-loaded sodium alginate hydrogel membranes supplemented with hydroxypropyl methylcellulose and hydroxypropyl cellulose polymers for wound dressing
por: Prabu, Durai, et al.
Publicado: (2016)

The use of complex formation manner for spectrophotometric analysis of gatifloxacin drug based on Co(II), Ni(II) and La(III) ions
por: Mostafa, Mona M., et al.
Publicado: (2021)

Efficacy and tolerability of a combined gatifloxacin plus prednisolone formulation for topical prophylaxis after LASIK
por: Campos, Mauro, et al.
Publicado: (2011)

Experimental and theoretical studies on the molecular properties of ciprofloxacin, norfloxacin, pefloxacin, sparfloxacin, and gatifloxacin in determining bioavailability
por: Kłosińska-Szmurło, E., et al.
Publicado: (2014)

In vivo 3D measurement of moxifloxacin and gatifloxacin distributions in the mouse cornea using multiphoton microscopy
por: Lee, Seunghun, et al.
Publicado: (2016)

Effects on the QT Interval of a Gatifloxacin-Containing Regimen versus Standard Treatment of Pulmonary Tuberculosis
por: Olliaro, Piero L., et al.
Publicado: (2017)

Dissipation Dynamics of Doxycycline and Gatifloxacin and Accumulation of Heavy Metals during Broiler Manure Aerobic Composting
por: Chu, Lei, et al.
Publicado: (2021)

Comparative Study of Ocular Pharmacokinetics of Topical 0.3% Gatifloxacin Eye Gel and Solution in Rabbits
por: Liu, Manli, et al.
Publicado: (2022)

Au nanoparticle sensitized blue TiO(2) nanorod arrays for efficient Gatifloxacin photodegradation
por: Guo, Jun, et al.
Publicado: (2023)

Characterization of PM(10) and Impact on Human Health During the Annual Festival of Lights (Diwali)
por: Garaga, Rajyalakshmi, et al.
Publicado: (2018)

Identification of anti-inflammatory and other biological activities of 3-carboxamide, 3-carbohydrazide and ester derivatives of gatifloxacin
por: Sultana, Najma, et al.
Publicado: (2013)

Gatifloxacin Versus Ofloxacin for the Treatment of Uncomplicated Enteric Fever in Nepal: An Open-Label, Randomized, Controlled Trial
por: Koirala, Samir, et al.
Publicado: (2013)

A Multi-Center Randomized Trial to Assess the Efficacy of Gatifloxacin versus Ciprofloxacin for the Treatment of Shigellosis in Vietnamese Children
por: Vinh, Ha, et al.
Publicado: (2011)

Gatifloxacin versus ceftriaxone for uncomplicated enteric fever in Nepal: an open-label, two-centre, randomised controlled trial
por: Arjyal, Amit, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n4fhrcrc20l1l63svq3ed9sneq