Cargando…
Partially Penetrant Postnatal Lethality of an Epithelial Specific MicroRNA in a Mouse Knockout
MicroRNAs are small noncoding RNAs thought to have pivotal roles in numerous diseases and developmental processes. However, a growing body of literature indicates that in vivo elimination of these tiny RNAs usually has little to no observable consequence, suggesting functional redundancy with other...
Autores principales: | Farmer, D’Juan T., Shariat, Nikki, Park, Chong Yon, Liu, Huey Jiin, Mavropoulos, Anastasia, McManus, Michael T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792019/ https://www.ncbi.nlm.nih.gov/pubmed/24116130 http://dx.doi.org/10.1371/journal.pone.0076634 |
Ejemplares similares
-
Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells
por: Khan, Imran S., et al.
Publicado: (2015) -
Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice
por: Wilson, Robert, et al.
Publicado: (2017) -
Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene
por: Fujihira, Haruhiko, et al.
Publicado: (2017) -
Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal
por: Krill-Burger, J. Michael, et al.
Publicado: (2023) -
Holocarboxylase synthetase knockout is embryonic lethal in mice
por: Sadri, Mahrou, et al.
Publicado: (2022)