Role of Cysteines in the Stability and DNA-Binding Activity of the Hypochlorite-Specific Transcription Factor HypT

Reactive oxygen species are important components of the immune response. Hypochlorite (HOCl) is produced by neutrophils to kill invading microorganisms. The bactericidal activity of HOCl is due to proteome-wide unfolding and oxidation of proteins at cysteine and methionine residues. Escherichia coli...

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Detalles Bibliográficos
Autores principales: Drazic, Adrian, Tsoutsoulopoulos, Amelie, Peschek, Jirka, Gundlach, Jasmin, Krause, Maike, Bach, Nina C., Gebendorfer, Katharina M., Winter, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792123/
https://www.ncbi.nlm.nih.gov/pubmed/24116067
http://dx.doi.org/10.1371/journal.pone.0075683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792123/
https://www.ncbi.nlm.nih.gov/pubmed/24116067
http://dx.doi.org/10.1371/journal.pone.0075683

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