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A Cocktail of Thermally Stable, Chemically Synthesized Capture Agents for the Efficient Detection of Anti-Gp41 Antibodies from Human Sera
We report on a method to improve in vitro diagnostic assays that detect immune response, with specific application to HIV-1. The inherent polyclonal diversity of the humoral immune response was addressed by using sequential in situ click chemistry to develop a cocktail of peptide-based capture agent...
Autores principales: | Pfeilsticker, Jessica A., Umeda, Aiko, Farrow, Blake, Hsueh, Connie L., Deyle, Kaycie M., Kim, Jocelyn T., Lai, Bert T., Heath, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792125/ https://www.ncbi.nlm.nih.gov/pubmed/24116098 http://dx.doi.org/10.1371/journal.pone.0076224 |
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