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Quantitative in silico Analysis of Neurotransmitter Pathways Under Steady State Conditions

The modeling of glutamate/GABA-glutamine cycling in the brain tissue involving astrocytes, glutamatergic and GABAergic neurons leads to a complex compartmentalized metabolic network that comprises neurotransmitter synthesis, shuttling, and degradation. Without advanced computational tools, it is dif...

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Detalles Bibliográficos
Autores principales: Calvetti, Daniela, Somersalo, Erkki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792486/
https://www.ncbi.nlm.nih.gov/pubmed/24115944
http://dx.doi.org/10.3389/fendo.2013.00137