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Structure of UreG/UreF/UreH Complex Reveals How Urease Accessory Proteins Facilitate Maturation of Helicobacter pylori Urease

Urease is a metalloenzyme essential for the survival of Helicobacter pylori in acidic gastric environment. Maturation of urease involves carbamylation of Lys219 and insertion of two nickel ions at its active site. This process requires GTP hydrolysis and the formation of a preactivation complex cons...

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Detalles Bibliográficos
Autores principales:	Fong, Yu Hang, Wong, Ho Chun, Yuen, Man Hon, Lau, Pak Ho, Chen, Yu Wai, Wong, Kam-Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792862/ https://www.ncbi.nlm.nih.gov/pubmed/24115911 http://dx.doi.org/10.1371/journal.pbio.1001678

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