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Epistatic Interactions between Apolipoprotein E and Hemoglobin S Genes in Regulation of Malaria Parasitemia

Apolipoprotein E is a monomeric protein secreted by the liver and responsible for the transport of plasma cholesterol and triglycerides. The APOE gene encodes 3 isoforms Ɛ4, Ɛ3 and Ɛ2 with APOE Ɛ4 associated with higher plasma cholesterol levels and increased pathogenesis in several infectious disea...

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Detalles Bibliográficos
Autores principales:	Rougeron, Virginie, Woods, Caira M., Tiedje, Kathryn E., Bodeau-Livinec, Florence, Migot-Nabias, Florence, Deloron, Philippe, Luty, Adrian J. F., Fowkes, Freya J. I., Day, Karen P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792892/ https://www.ncbi.nlm.nih.gov/pubmed/24116184 http://dx.doi.org/10.1371/journal.pone.0076924

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