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Escherichia coli Producing Colibactin Triggers Premature and Transmissible Senescence in Mammalian Cells
Cellular senescence is an irreversible state of proliferation arrest evoked by a myriad of stresses including oncogene activation, telomere shortening/dysfunction and genotoxic insults. It has been associated with tumor activation, immune suppression and aging, owing to the secretion of proinflammat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792898/ https://www.ncbi.nlm.nih.gov/pubmed/24116215 http://dx.doi.org/10.1371/journal.pone.0077157 |