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HIV-1 Vpr Induces the Degradation of ZIP and sZIP, Adaptors of the NuRD Chromatin Remodeling Complex, by Hijacking DCAF1/VprBP
The Vpr protein from type 1 and type 2 Human Immunodeficiency Viruses (HIV-1 and HIV-2) is thought to inactivate several host proteins through the hijacking of the DCAF1 adaptor of the Cul4A ubiquitin ligase. Here, we identified two transcriptional regulators, ZIP and sZIP, as Vpr-binding proteins d...
Autores principales: | Maudet, Claire, Sourisce, Adèle, Dragin, Loïc, Lahouassa, Hichem, Rain, Jean-Christophe, Bouaziz, Serge, Ramirez, Bertha Cécilia, Margottin-Goguet, Florence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792905/ https://www.ncbi.nlm.nih.gov/pubmed/24116224 http://dx.doi.org/10.1371/journal.pone.0077320 |
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