Cargando…

A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity

RNA interference defends against viral infection in plant and animal cells. The nematode Caenorhabditis elegans and its natural pathogen, the positive-strand RNA virus Orsay, have recently emerged as a new animal model of host-virus interaction. Using a genome-wide association study in C. elegans wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ashe, Alyson, Bélicard, Tony, Le Pen, Jérémie, Sarkies, Peter, Frézal, Lise, Lehrbach, Nicolas J, Félix, Marie-Anne, Miska, Eric A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2013
Materias:	Genomics and Evolutionary Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793227/ https://www.ncbi.nlm.nih.gov/pubmed/24137537 http://dx.doi.org/10.7554/eLife.00994

Ejemplares similares

Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans
por: Ashe, Alyson, et al.
Publicado: (2015)

Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegans
por: Sarkies, Peter, et al.
Publicado: (2013)

piRNAs Can Trigger a Multigenerational Epigenetic Memory in the Germline of C. elegans
por: Ashe, Alyson, et al.
Publicado: (2012)

Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs
por: Coffman, Stephanie R., et al.
Publicado: (2017)

Tertiary siRNAs Mediate Paramutation in C. elegans
por: Sapetschnig, Alexandra, et al.
Publicado: (2015)

An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans
por: Tanguy, Mélanie, et al.
Publicado: (2017)

Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations
por: Crombie, Tim A, et al.
Publicado: (2019)

Natural and Experimental Infection of Caenorhabditis Nematodes by Novel Viruses Related to Nodaviruses
por: Félix, Marie-Anne, et al.
Publicado: (2011)

A biphasic model of lifespan in nematode Caenorhabditis elegans worm
por: Mulla, Suhayl, et al.
Publicado: (2023)

Changes to social feeding behaviors are not sufficient for fitness gains of the Caenorhabditis elegans N2 reference strain
por: Zhao, Yuehui, et al.
Publicado: (2018)

An RIG-I-Like RNA Helicase Mediates Antiviral RNAi Downstream of Viral siRNA Biogenesis in Caenorhabditis elegans
por: Lu, Rui, et al.
Publicado: (2009)

Control of Locomotory Behavior of Caenorhabditis elegans by the Immunoglobulin Superfamily Protein RIG-3
por: Bhardwaj, Ashwani, et al.
Publicado: (2020)

Caenorhabditis elegans and friends in Los Angeles
por: Alvarez-Saavedra, Ezequiel A, et al.
Publicado: (2005)

Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response
por: Mao, Kai, et al.
Publicado: (2020)

Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state
por: Rahman, Kazi, et al.
Publicado: (2020)

C. elegans outside the Petri dish
por: Frézal, Lise, et al.
Publicado: (2015)

Canalisation and plasticity on the developmental manifold of Caenorhabditis elegans
por: Jordan, David J, et al.
Publicado: (2023)

Digital dissection of the pelvis and hindlimb of the red-legged running frog, Phlyctimantis maculatus, using Diffusible Iodine Contrast Enhanced computed microtomography (DICE μCT)
por: Collings, Amber J., et al.
Publicado: (2019)

Regulation of WNT Signaling at the Neuromuscular Junction by the Immunoglobulin Superfamily Protein RIG-3 in Caenorhabditis elegans
por: Pandey, Pratima, et al.
Publicado: (2017)

Selfing is the safest sex for Caenorhabditis tropicalis
por: Noble, Luke M, et al.
Publicado: (2021)

E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans
por: Akay, Alper, et al.
Publicado: (2015)

Slicing and dicing viruses: antiviral RNA interference in mammals
por: Maillard, Pierre V, et al.
Publicado: (2019)

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans
por: Lehrbach, Nicolas J., et al.
Publicado: (2009)

Differential Impact of the HEN1 Homolog HENN-1 on 21U and 26G RNAs in the Germline of Caenorhabditis elegans
por: Kamminga, Leonie M., et al.
Publicado: (2012)

The piRNA pathway responds to environmental signals to establish intergenerational adaptation to stress
por: Belicard, Tony, et al.
Publicado: (2018)

Loss of the E3 ubiquitin ligases UBR-5 or HECD-1 restores Caenorhabditis elegans development in the absence of SWI/SNF function
por: Lampersberger, Lisa, et al.
Publicado: (2023)

RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans
por: Akay, Alper, et al.
Publicado: (2013)

The RNA polymerase II subunit RPB‐9 recruits the integrator complex to terminate Caenorhabditis elegans piRNA transcription
por: Berkyurek, Ahmet C, et al.
Publicado: (2021)

Efficient genome editing in Caenorhabditis elegans by CRISPR-targeted homologous recombination
por: Chen, Changchun, et al.
Publicado: (2013)

Structural and functional analysis of SMO-1, the SUMO homolog in Caenorhabditis elegans
por: Surana, Parag, et al.
Publicado: (2017)

An atonal homolog, lin-32, regulates hypodermal morphogenesis in Caenorhabditis elegans
por: Hori, Sayaka, et al.
Publicado: (2023)

Noda-Like RNA Viruses Infecting Caenorhabditis Nematodes: Sympatry, Diversity, and Reassortment
por: Frézal, Lise, et al.
Publicado: (2019)

Nongenetic inheritance and multigenerational plasticity in the nematode C. elegans
por: Baugh, L Ryan, et al.
Publicado: (2020)

Balancing selection on genomic deletion polymorphisms in humans
por: Aqil, Alber, et al.
Publicado: (2023)

Deletion of Thioredoxin Reductase and Effects of Selenite and Selenate Toxicity in Caenorhabditis elegans
por: Boehler, Christopher J., et al.
Publicado: (2013)

CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans
por: Au, Vinci, et al.
Publicado: (2018)

Fast genetic mapping using insertion-deletion polymorphisms in Caenorhabditis elegans
por: Hwang, Ho-Yon, et al.
Publicado: (2021)

Mushroom body evolution demonstrates homology and divergence across Pancrustacea
por: Strausfeld, Nicholas James, et al.
Publicado: (2020)

Evolutionary conflicts and adverse effects of antiviral factors
por: Sauter, Daniel, et al.
Publicado: (2021)

The turn of the dice: Patrick Hughes’ Hollow Dice and Reverspectives
por: Rogers, Brian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2n238qis54cek8qiijqefsk0e0