Extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: A report of two cases

Extramedullary hematopoiesis (EMH) evidenced by erythropoietic cells and megakaryocytes is a characteristic feature of hepatoblastoma (HB). The typical cytomorphology, the presence of EMH and associated clinical and radiological findings offer a reliable diagnosis of hepatoblastoma by fine-needle as...

Descripción completa

Detalles Bibliográficos
Autores principales: Thambi, Renu, Devi, Lekshmi, Balachandran, Krishna, Poothiode, Usha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793359/
https://www.ncbi.nlm.nih.gov/pubmed/24130414
http://dx.doi.org/10.4103/0970-9371.117643
_version_ 1782286957393477632
author Thambi, Renu
Devi, Lekshmi
Balachandran, Krishna
Poothiode, Usha
author_facet Thambi, Renu
Devi, Lekshmi
Balachandran, Krishna
Poothiode, Usha
author_sort Thambi, Renu
collection PubMed
description Extramedullary hematopoiesis (EMH) evidenced by erythropoietic cells and megakaryocytes is a characteristic feature of hepatoblastoma (HB). The typical cytomorphology, the presence of EMH and associated clinical and radiological findings offer a reliable diagnosis of hepatoblastoma by fine-needle aspiration cytology (FNAC). We describe the cytologic features of hepatoblastomas and discuss the differential diagnosis in two children, aged 53 days and 19 years. The usefulness of EMH in differentiating HB from other small round cell tumors and well differentiated hepatocellular carcinoma (HCC) on cytology is highlighted.
format Online
Article
Text
id pubmed-3793359
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-37933592013-10-15 Extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: A report of two cases Thambi, Renu Devi, Lekshmi Balachandran, Krishna Poothiode, Usha J Cytol Case Report Extramedullary hematopoiesis (EMH) evidenced by erythropoietic cells and megakaryocytes is a characteristic feature of hepatoblastoma (HB). The typical cytomorphology, the presence of EMH and associated clinical and radiological findings offer a reliable diagnosis of hepatoblastoma by fine-needle aspiration cytology (FNAC). We describe the cytologic features of hepatoblastomas and discuss the differential diagnosis in two children, aged 53 days and 19 years. The usefulness of EMH in differentiating HB from other small round cell tumors and well differentiated hepatocellular carcinoma (HCC) on cytology is highlighted. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3793359/ /pubmed/24130414 http://dx.doi.org/10.4103/0970-9371.117643 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Thambi, Renu
Devi, Lekshmi
Balachandran, Krishna
Poothiode, Usha
Extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: A report of two cases
title Extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: A report of two cases
title_full Extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: A report of two cases
title_fullStr Extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: A report of two cases
title_full_unstemmed Extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: A report of two cases
title_short Extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: A report of two cases
title_sort extramedullary hematopoiesis as a ‘clue’ to diagnosis of hepatoblastoma on fine needle aspiration cytology: a report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793359/
https://www.ncbi.nlm.nih.gov/pubmed/24130414
http://dx.doi.org/10.4103/0970-9371.117643
work_keys_str_mv AT thambirenu extramedullaryhematopoiesisasacluetodiagnosisofhepatoblastomaonfineneedleaspirationcytologyareportoftwocases
AT devilekshmi extramedullaryhematopoiesisasacluetodiagnosisofhepatoblastomaonfineneedleaspirationcytologyareportoftwocases
AT balachandrankrishna extramedullaryhematopoiesisasacluetodiagnosisofhepatoblastomaonfineneedleaspirationcytologyareportoftwocases
AT poothiodeusha extramedullaryhematopoiesisasacluetodiagnosisofhepatoblastomaonfineneedleaspirationcytologyareportoftwocases

Ejemplares similares