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Evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis

BACKGROUND: To evaluate gingival crevicular fluid (GCF) and salivary cortisol levels in anxious and non-anxious patients with chronic periodontitis. MATERIALS AND METHODS: A total of 45 patients with a mean age 43.4 ± 6.12 years were assigned to three groups: Healthy control group (Group 1), group w...

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Autores principales: Nayak, Sangeeta Umesh, Nayak, Dilip G., Uppoor, Ashita S., Pai, K. Keshava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793410/
https://www.ncbi.nlm.nih.gov/pubmed/24130582
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author Nayak, Sangeeta Umesh
Nayak, Dilip G.
Uppoor, Ashita S.
Pai, K. Keshava
author_facet Nayak, Sangeeta Umesh
Nayak, Dilip G.
Uppoor, Ashita S.
Pai, K. Keshava
author_sort Nayak, Sangeeta Umesh
collection PubMed
description BACKGROUND: To evaluate gingival crevicular fluid (GCF) and salivary cortisol levels in anxious and non-anxious patients with chronic periodontitis. MATERIALS AND METHODS: A total of 45 patients with a mean age 43.4 ± 6.12 years were assigned to three groups: Healthy control group (Group 1), group with chronic periodontitis but no anxiety (Group 2) and group with chronic periodontitis and with anxiety (Group 3). State – Trait anxiety inventory and Hamilton Anxiety rating scale were used to assess the anxiety levels of all the subjects. Clinical measures such as plaque index (PI), gingival index (GI), probing pocket depth (PPD) and clinical attachment level (CAL) were recorded. GCF and unstimulated whole saliva samples were collected, and cortisol levels were determined using ELISA kit. RESULTS: PI, GI, PPD, and CAL were higher in Group 3. Hormone level was significantly higher in Group 3. A positive correlation was found among salivary and GCF cortisol and CAL in Group 3. CONCLUSION: Based on the obtained results individuals with high-levels of anxiety seem to be more prone to have periodontal disease. Salivary and GCF cortisol levels can be used as biomarker for evaluating part of the etiopathogenesis of chronic periodontitis.
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spelling pubmed-37934102013-10-15 Evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis Nayak, Sangeeta Umesh Nayak, Dilip G. Uppoor, Ashita S. Pai, K. Keshava Dent Res J (Isfahan) Original Article BACKGROUND: To evaluate gingival crevicular fluid (GCF) and salivary cortisol levels in anxious and non-anxious patients with chronic periodontitis. MATERIALS AND METHODS: A total of 45 patients with a mean age 43.4 ± 6.12 years were assigned to three groups: Healthy control group (Group 1), group with chronic periodontitis but no anxiety (Group 2) and group with chronic periodontitis and with anxiety (Group 3). State – Trait anxiety inventory and Hamilton Anxiety rating scale were used to assess the anxiety levels of all the subjects. Clinical measures such as plaque index (PI), gingival index (GI), probing pocket depth (PPD) and clinical attachment level (CAL) were recorded. GCF and unstimulated whole saliva samples were collected, and cortisol levels were determined using ELISA kit. RESULTS: PI, GI, PPD, and CAL were higher in Group 3. Hormone level was significantly higher in Group 3. A positive correlation was found among salivary and GCF cortisol and CAL in Group 3. CONCLUSION: Based on the obtained results individuals with high-levels of anxiety seem to be more prone to have periodontal disease. Salivary and GCF cortisol levels can be used as biomarker for evaluating part of the etiopathogenesis of chronic periodontitis. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3793410/ /pubmed/24130582 Text en Copyright: © Dental Research Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Nayak, Sangeeta Umesh
Nayak, Dilip G.
Uppoor, Ashita S.
Pai, K. Keshava
Evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis
title Evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis
title_full Evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis
title_fullStr Evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis
title_full_unstemmed Evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis
title_short Evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis
title_sort evaluation of cortisol levels in gingival crevicular fluid and saliva in anxious and non-anxious patients with chronic periodontitis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793410/
https://www.ncbi.nlm.nih.gov/pubmed/24130582
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