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Clinical experimentation with aerosol antibiotics: current and future methods of administration

Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form i...

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Autores principales: Zarogoulidis, Paul, Kioumis, Ioannis, Porpodis, Konstantinos, Spyratos, Dionysios, Tsakiridis, Kosmas, Huang, Haidong, Li, Qiang, Turner, J Francis, Browning, Robert, Hohenforst-Schmidt, Wolfgang, Zarogoulidis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793595/
https://www.ncbi.nlm.nih.gov/pubmed/24115836
http://dx.doi.org/10.2147/DDDT.S51303
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author Zarogoulidis, Paul
Kioumis, Ioannis
Porpodis, Konstantinos
Spyratos, Dionysios
Tsakiridis, Kosmas
Huang, Haidong
Li, Qiang
Turner, J Francis
Browning, Robert
Hohenforst-Schmidt, Wolfgang
Zarogoulidis, Konstantinos
author_facet Zarogoulidis, Paul
Kioumis, Ioannis
Porpodis, Konstantinos
Spyratos, Dionysios
Tsakiridis, Kosmas
Huang, Haidong
Li, Qiang
Turner, J Francis
Browning, Robert
Hohenforst-Schmidt, Wolfgang
Zarogoulidis, Konstantinos
author_sort Zarogoulidis, Paul
collection PubMed
description Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.
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spelling pubmed-37935952013-10-10 Clinical experimentation with aerosol antibiotics: current and future methods of administration Zarogoulidis, Paul Kioumis, Ioannis Porpodis, Konstantinos Spyratos, Dionysios Tsakiridis, Kosmas Huang, Haidong Li, Qiang Turner, J Francis Browning, Robert Hohenforst-Schmidt, Wolfgang Zarogoulidis, Konstantinos Drug Des Devel Ther Review Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed. Dove Medical Press 2013-10-02 /pmc/articles/PMC3793595/ /pubmed/24115836 http://dx.doi.org/10.2147/DDDT.S51303 Text en © 2013 Zarogoulidis et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Zarogoulidis, Paul
Kioumis, Ioannis
Porpodis, Konstantinos
Spyratos, Dionysios
Tsakiridis, Kosmas
Huang, Haidong
Li, Qiang
Turner, J Francis
Browning, Robert
Hohenforst-Schmidt, Wolfgang
Zarogoulidis, Konstantinos
Clinical experimentation with aerosol antibiotics: current and future methods of administration
title Clinical experimentation with aerosol antibiotics: current and future methods of administration
title_full Clinical experimentation with aerosol antibiotics: current and future methods of administration
title_fullStr Clinical experimentation with aerosol antibiotics: current and future methods of administration
title_full_unstemmed Clinical experimentation with aerosol antibiotics: current and future methods of administration
title_short Clinical experimentation with aerosol antibiotics: current and future methods of administration
title_sort clinical experimentation with aerosol antibiotics: current and future methods of administration
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793595/
https://www.ncbi.nlm.nih.gov/pubmed/24115836
http://dx.doi.org/10.2147/DDDT.S51303
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