4-Chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate

The title compound, C(25)H(26)Cl(2)FN(3)O(4)S, contains two bio-active moieties (thio­barbituric acid and fluoro­quinolone). In the crystal, mol­ecules are linked via C—H⋯O and C—H⋯F hydrogen bonds, forming two-dimensional slab-like networks lying parallel to the bc plane. The benzene ring substitut...

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Detalles Bibliográficos
Autores principales: Sweidan, Kamal, Haddad, Salim F., AlDamen, Murad A., Al-Sheikhb, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793705/
https://www.ncbi.nlm.nih.gov/pubmed/24109292
http://dx.doi.org/10.1107/S1600536813016024
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author Sweidan, Kamal
Haddad, Salim F.
AlDamen, Murad A.
Al-Sheikhb, Ahmed
author_facet Sweidan, Kamal
Haddad, Salim F.
AlDamen, Murad A.
Al-Sheikhb, Ahmed
author_sort Sweidan, Kamal
collection PubMed
description The title compound, C(25)H(26)Cl(2)FN(3)O(4)S, contains two bio-active moieties (thio­barbituric acid and fluoro­quinolone). In the crystal, mol­ecules are linked via C—H⋯O and C—H⋯F hydrogen bonds, forming two-dimensional slab-like networks lying parallel to the bc plane. The benzene ring substituted by F and Cl atoms and the 4-chloro­butyl group seem to be partly disordered, however attempts to model the disorder were unsuccessful.
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spelling pubmed-37937052013-10-09 4-Chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate Sweidan, Kamal Haddad, Salim F. AlDamen, Murad A. Al-Sheikhb, Ahmed Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(25)H(26)Cl(2)FN(3)O(4)S, contains two bio-active moieties (thio­barbituric acid and fluoro­quinolone). In the crystal, mol­ecules are linked via C—H⋯O and C—H⋯F hydrogen bonds, forming two-dimensional slab-like networks lying parallel to the bc plane. The benzene ring substituted by F and Cl atoms and the 4-chloro­butyl group seem to be partly disordered, however attempts to model the disorder were unsuccessful. International Union of Crystallography 2013-07-03 /pmc/articles/PMC3793705/ /pubmed/24109292 http://dx.doi.org/10.1107/S1600536813016024 Text en © Sweidan et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Sweidan, Kamal
Haddad, Salim F.
AlDamen, Murad A.
Al-Sheikhb, Ahmed
4-Chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate
title 4-Chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate
title_full 4-Chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate
title_fullStr 4-Chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate
title_full_unstemmed 4-Chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate
title_short 4-Chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate
title_sort 4-chloro­butyl 7-chloro-1-cyclo­propyl-4-(1,3-diethyl-4,6-dioxo-2-sulfanyl­idene-1,3-diazinan-5-yl­idene)-6-fluoro-1,4-di­hydro­quinoline-3-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793705/
https://www.ncbi.nlm.nih.gov/pubmed/24109292
http://dx.doi.org/10.1107/S1600536813016024
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AT aldamenmurada 4chlorobutyl7chloro1cyclopropyl413diethyl46dioxo2sulfanylidene13diazinan5ylidene6fluoro14dihydroquinoline3carboxylate
AT alsheikhbahmed 4chlorobutyl7chloro1cyclopropyl413diethyl46dioxo2sulfanylidene13diazinan5ylidene6fluoro14dihydroquinoline3carboxylate

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