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5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide

In the title compound, C(24)H(24)FN(3)O(2)S, the 1,3-thia­zolidine ring adopts an envelope conformation with the S atom as the flap, while the cyclo­hexane ring is in a chair conformation. In the crystal, mol­ecules are linked by N—H⋯O and C—H⋯F hydrogen bonds, forming a three-dimensional network. T...

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Detalles Bibliográficos
Autores principales: Çelikesir, Sevim Türktekin, Akkurt, Mehmet, Üstündağ, Gökçe Cihan, Büyükgüngör, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793733/
https://www.ncbi.nlm.nih.gov/pubmed/24109320
http://dx.doi.org/10.1107/S1600536813018576
Descripción
Sumario:In the title compound, C(24)H(24)FN(3)O(2)S, the 1,3-thia­zolidine ring adopts an envelope conformation with the S atom as the flap, while the cyclo­hexane ring is in a chair conformation. In the crystal, mol­ecules are linked by N—H⋯O and C—H⋯F hydrogen bonds, forming a three-dimensional network. The unit cell contains six voids of 57 Å(3), but the residual electron density (highest peak = 0.23 e Å(−3) and deepest hole = −0.19 e Å(−3)) in the difference Fourier map suggests no solvent mol­ecule occupies this void.