5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide

In the title compound, C(24)H(24)FN(3)O(2)S, the 1,3-thia­zolidine ring adopts an envelope conformation with the S atom as the flap, while the cyclo­hexane ring is in a chair conformation. In the crystal, mol­ecules are linked by N—H⋯O and C—H⋯F hydrogen bonds, forming a three-dimensional network. T...

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Autores principales: Çelikesir, Sevim Türktekin, Akkurt, Mehmet, Üstündağ, Gökçe Cihan, Büyükgüngör, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793733/
https://www.ncbi.nlm.nih.gov/pubmed/24109320
http://dx.doi.org/10.1107/S1600536813018576
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author Çelikesir, Sevim Türktekin
Akkurt, Mehmet
Üstündağ, Gökçe Cihan
Büyükgüngör, Orhan
author_facet Çelikesir, Sevim Türktekin
Akkurt, Mehmet
Üstündağ, Gökçe Cihan
Büyükgüngör, Orhan
author_sort Çelikesir, Sevim Türktekin
collection PubMed
description In the title compound, C(24)H(24)FN(3)O(2)S, the 1,3-thia­zolidine ring adopts an envelope conformation with the S atom as the flap, while the cyclo­hexane ring is in a chair conformation. In the crystal, mol­ecules are linked by N—H⋯O and C—H⋯F hydrogen bonds, forming a three-dimensional network. The unit cell contains six voids of 57 Å(3), but the residual electron density (highest peak = 0.23 e Å(−3) and deepest hole = −0.19 e Å(−3)) in the difference Fourier map suggests no solvent mol­ecule occupies this void.
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spelling pubmed-37937332013-10-09 5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide Çelikesir, Sevim Türktekin Akkurt, Mehmet Üstündağ, Gökçe Cihan Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(24)FN(3)O(2)S, the 1,3-thia­zolidine ring adopts an envelope conformation with the S atom as the flap, while the cyclo­hexane ring is in a chair conformation. In the crystal, mol­ecules are linked by N—H⋯O and C—H⋯F hydrogen bonds, forming a three-dimensional network. The unit cell contains six voids of 57 Å(3), but the residual electron density (highest peak = 0.23 e Å(−3) and deepest hole = −0.19 e Å(−3)) in the difference Fourier map suggests no solvent mol­ecule occupies this void. International Union of Crystallography 2013-07-10 /pmc/articles/PMC3793733/ /pubmed/24109320 http://dx.doi.org/10.1107/S1600536813018576 Text en © Çelikesir et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Çelikesir, Sevim Türktekin
Akkurt, Mehmet
Üstündağ, Gökçe Cihan
Büyükgüngör, Orhan
5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide
title 5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide
title_full 5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide
title_fullStr 5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide
title_full_unstemmed 5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide
title_short 5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide
title_sort 5-fluoro-n-(2-methyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-3-phenyl-1h-indole-2-carboxamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793733/
https://www.ncbi.nlm.nih.gov/pubmed/24109320
http://dx.doi.org/10.1107/S1600536813018576
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