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2,2-Diphenyl-N-{[2-(trifluoromethyl)phenyl]carbamothioyl}acetamide
The title molecule, C(22)H(17)F(3)N(2)OS, adopts a trans–cis conformation with respect to the positions of the carbonyl and trifluoromethylbenzene groups against the thiocarbonyl group across the C—N bonds. The molecular structure is stabilized by an intramolecular N—H⋯O hydrogen bond with an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793754/ https://www.ncbi.nlm.nih.gov/pubmed/24109341 http://dx.doi.org/10.1107/S1600536813018680 |
Sumario: | The title molecule, C(22)H(17)F(3)N(2)OS, adopts a trans–cis conformation with respect to the positions of the carbonyl and trifluoromethylbenzene groups against the thiocarbonyl group across the C—N bonds. The molecular structure is stabilized by an intramolecular N—H⋯O hydrogen bond with an S(6) ring motif. The trifluoromethyl-substituted benzene ring forms dihedral angles of 66.05 (9) and 47.19 (9)° with the terminal phenyl rings and is twisted from the O=C—N—(C=S)—N carbonylthiourea plane [maximum deviation = 0.0535 (12) Å], making a dihedral angle of 63.59 (8)°. In the crystal, N—H⋯O and C—H⋯F hydrogen bonds link the molecules into a layer parallel to the bc plane. A C—H⋯π interaction is also observed. |
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