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1-Ethyl-4′-(1H-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate

In the title compound, C(31)H(25)N(5)O(3)·C(2)H(6)OS, the three indole/indoline units are all essentially planar with maximum deviations of 0.0172 (3), 0.053 (2) and 0.07 (2) Å. The pyrrolidine ring adopts an envelope conformation with the C atoms bearing the 1-ethyl-2-oxo­indole substituent (in whi...

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Autores principales: Inglebert, S. Antony, Arun, Yuvaraj, Sethusankar, K., Perumal, Paramasivam T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793813/
https://www.ncbi.nlm.nih.gov/pubmed/24109400
http://dx.doi.org/10.1107/S1600536813020485
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author Inglebert, S. Antony
Arun, Yuvaraj
Sethusankar, K.
Perumal, Paramasivam T.
author_facet Inglebert, S. Antony
Arun, Yuvaraj
Sethusankar, K.
Perumal, Paramasivam T.
author_sort Inglebert, S. Antony
collection PubMed
description In the title compound, C(31)H(25)N(5)O(3)·C(2)H(6)OS, the three indole/indoline units are all essentially planar with maximum deviations of 0.0172 (3), 0.053 (2) and 0.07 (2) Å. The pyrrolidine ring adopts an envelope conformation with the C atoms bearing the 1-ethyl-2-oxo­indole substituent (in which the five-membered ring adopts a twisted conformation) as the flap. The dimethyl sulfoxide solvent mol­ecule is disordered over two positions, with an occupancy factor ratio of 0.871 (4):0.129 (4). The solvent components are linked to the heterocyclic mol­ecule via C—H⋯O and C—H⋯S hydrogen bonds. In the crystal, the solvent components are linked to the heterocyclic molecule via C—H⋯O and C—H⋯S inter­actions, forming R (2) (2)(10) ring motifs. The mol­ecules are further connected into a chain along the a-axis direction via N—H⋯O hydrogen bonds.
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spelling pubmed-37938132013-10-09 1-Ethyl-4′-(1H-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate Inglebert, S. Antony Arun, Yuvaraj Sethusankar, K. Perumal, Paramasivam T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(31)H(25)N(5)O(3)·C(2)H(6)OS, the three indole/indoline units are all essentially planar with maximum deviations of 0.0172 (3), 0.053 (2) and 0.07 (2) Å. The pyrrolidine ring adopts an envelope conformation with the C atoms bearing the 1-ethyl-2-oxo­indole substituent (in which the five-membered ring adopts a twisted conformation) as the flap. The dimethyl sulfoxide solvent mol­ecule is disordered over two positions, with an occupancy factor ratio of 0.871 (4):0.129 (4). The solvent components are linked to the heterocyclic mol­ecule via C—H⋯O and C—H⋯S hydrogen bonds. In the crystal, the solvent components are linked to the heterocyclic molecule via C—H⋯O and C—H⋯S inter­actions, forming R (2) (2)(10) ring motifs. The mol­ecules are further connected into a chain along the a-axis direction via N—H⋯O hydrogen bonds. International Union of Crystallography 2013-07-27 /pmc/articles/PMC3793813/ /pubmed/24109400 http://dx.doi.org/10.1107/S1600536813020485 Text en © Inglebert et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Inglebert, S. Antony
Arun, Yuvaraj
Sethusankar, K.
Perumal, Paramasivam T.
1-Ethyl-4′-(1H-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate
title 1-Ethyl-4′-(1H-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate
title_full 1-Ethyl-4′-(1H-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate
title_fullStr 1-Ethyl-4′-(1H-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate
title_full_unstemmed 1-Ethyl-4′-(1H-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate
title_short 1-Ethyl-4′-(1H-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate
title_sort 1-ethyl-4′-(1h-indol-3-ylcarbon­yl)-1′-methyl-2,2′′-dioxodi­spiro­[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carbo­nitrile dimethyl sulfoxide monosolvate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793813/
https://www.ncbi.nlm.nih.gov/pubmed/24109400
http://dx.doi.org/10.1107/S1600536813020485
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AT arunyuvaraj 1ethyl41hindol3ylcarbonyl1methyl22dioxodispiroindoline32pyrrolidine33indoline4carbonitriledimethylsulfoxidemonosolvate
AT sethusankark 1ethyl41hindol3ylcarbonyl1methyl22dioxodispiroindoline32pyrrolidine33indoline4carbonitriledimethylsulfoxidemonosolvate
AT perumalparamasivamt 1ethyl41hindol3ylcarbonyl1methyl22dioxodispiroindoline32pyrrolidine33indoline4carbonitriledimethylsulfoxidemonosolvate