Flunarizinium hydrogen maleate

In the cation of the title salt {systematic name: 4-[bis­(4-fluoro­phen­yl)meth­yl]-1-[(2E)-3-phenyl­prop-2-en-1-yl]piperazin-1-ium hydrogen maleate}, C(26)H(27)F(2)N(2) (+)·C(4)H(3)O(4) (−), the protonated piperazine ring is in a chair conformation. The dihedral angle between the 4-fluoro­phenyl ri...

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Detalles Bibliográficos
Autores principales: Kavitha, Channappa N., Jasinski, Jerry P., Matar, Somer M., Yathirajan, H. S., Ramesha, A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793824/
https://www.ncbi.nlm.nih.gov/pubmed/24109411
http://dx.doi.org/10.1107/S1600536813020291
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author Kavitha, Channappa N.
Jasinski, Jerry P.
Matar, Somer M.
Yathirajan, H. S.
Ramesha, A. R.
author_facet Kavitha, Channappa N.
Jasinski, Jerry P.
Matar, Somer M.
Yathirajan, H. S.
Ramesha, A. R.
author_sort Kavitha, Channappa N.
collection PubMed
description In the cation of the title salt {systematic name: 4-[bis­(4-fluoro­phen­yl)meth­yl]-1-[(2E)-3-phenyl­prop-2-en-1-yl]piperazin-1-ium hydrogen maleate}, C(26)H(27)F(2)N(2) (+)·C(4)H(3)O(4) (−), the protonated piperazine ring is in a chair conformation. The dihedral angle between the 4-fluoro­phenyl rings is 68.2 (2)°. An intra­molecular O—H⋯O hydrogen bond occurs in the anion. In the crystal, N—H⋯O, C—H⋯O and C—H⋯F inter­actions are observed, which link the ions into [001] chains.
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spelling pubmed-37938242013-10-09 Flunarizinium hydrogen maleate Kavitha, Channappa N. Jasinski, Jerry P. Matar, Somer M. Yathirajan, H. S. Ramesha, A. R. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the cation of the title salt {systematic name: 4-[bis­(4-fluoro­phen­yl)meth­yl]-1-[(2E)-3-phenyl­prop-2-en-1-yl]piperazin-1-ium hydrogen maleate}, C(26)H(27)F(2)N(2) (+)·C(4)H(3)O(4) (−), the protonated piperazine ring is in a chair conformation. The dihedral angle between the 4-fluoro­phenyl rings is 68.2 (2)°. An intra­molecular O—H⋯O hydrogen bond occurs in the anion. In the crystal, N—H⋯O, C—H⋯O and C—H⋯F inter­actions are observed, which link the ions into [001] chains. International Union of Crystallography 2013-07-27 /pmc/articles/PMC3793824/ /pubmed/24109411 http://dx.doi.org/10.1107/S1600536813020291 Text en © Kavitha et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Kavitha, Channappa N.
Jasinski, Jerry P.
Matar, Somer M.
Yathirajan, H. S.
Ramesha, A. R.
Flunarizinium hydrogen maleate
title Flunarizinium hydrogen maleate
title_full Flunarizinium hydrogen maleate
title_fullStr Flunarizinium hydrogen maleate
title_full_unstemmed Flunarizinium hydrogen maleate
title_short Flunarizinium hydrogen maleate
title_sort flunarizinium hydrogen maleate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793824/
https://www.ncbi.nlm.nih.gov/pubmed/24109411
http://dx.doi.org/10.1107/S1600536813020291
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AT rameshaar flunariziniumhydrogenmaleate

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