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Cysteine Residues in the Major Capsid Protein, Vp1, of the JC Virus Are Important for Protein Stability and Oligomer Formation

The capsid of the human polyomavirus JC virus (JCV) consists of 72 pentameric capsomeres of a major structural protein, Vp1. The cysteine residues of the related Vp1 of SV40 are known to contribute to Vp1 folding, pentamer formation, pentamer-pentamer contacts, and capsid stabilization. In light of...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Shintaro, Suzuki, Tadaki, Igarashi, Manabu, Orba, Yasuko, Ohtake, Noriko, Nagakawa, Keita, Niikura, Kenichi, Kimura, Takashi, Kasamatsu, Harumi, Sawa, Hirofumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793911/ https://www.ncbi.nlm.nih.gov/pubmed/24130786 http://dx.doi.org/10.1371/journal.pone.0076668

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