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IGF-IR Promotes Prostate Cancer Growth by Stabilizing α(5)β(1) Integrin Protein Levels

Dynamic crosstalk between growth factor receptors, cell adhesion molecules and extracellular matrix is essential for cancer cell migration and invasion. Integrins are transmembrane receptors that bind extracellular matrix proteins and enable cell adhesion and cytoskeletal organization. They also med...

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Detalles Bibliográficos
Autores principales: Sayeed, Aejaz, Fedele, Carmine, Trerotola, Marco, Ganguly, Kirat K., Languino, Lucia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793919/
https://www.ncbi.nlm.nih.gov/pubmed/24130778
http://dx.doi.org/10.1371/journal.pone.0076513

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