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Solution NMR Structure and Histone Binding of the PHD Domain of Human MLL5

Mixed Lineage Leukemia 5 (MLL5) is a histone methyltransferase that plays a key role in hematopoiesis, spermatogenesis and cell cycle progression. In addition to its catalytic domain, MLL5 contains a PHD finger domain, a protein module that is often involved in binding to the N-terminus of histone H...

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Detalles Bibliográficos
Autores principales:	Lemak, Alexander, Yee, Adelinda, Wu, Hong, Yap, Damian, Zeng, Hong, Dombrovski, Ludmila, Houliston, Scott, Aparicio, Samuel, Arrowsmith, Cheryl H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793974/ https://www.ncbi.nlm.nih.gov/pubmed/24130829 http://dx.doi.org/10.1371/journal.pone.0077020

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