Regression of Fibrosis and Reversal of Cirrhosis in Rats by Galectin Inhibitors in Thioacetamide-Induced Liver Disease

Galectin-3 protein is critical to the development of liver fibrosis because galectin-3 null mice have attenuated fibrosis after liver injury. Therefore, we examined the ability of novel complex carbohydrate galectin inhibitors to treat toxin-induced fibrosis and cirrhosis. Fibrosis was induced in ra...

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Detalles Bibliográficos
Autores principales: Traber, Peter G., Chou, Hsin, Zomer, Eliezer, Hong, Feng, Klyosov, Anatole, Fiel, Maria-Isabel, Friedman, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793988/
https://www.ncbi.nlm.nih.gov/pubmed/24130706
http://dx.doi.org/10.1371/journal.pone.0075361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793988/
https://www.ncbi.nlm.nih.gov/pubmed/24130706
http://dx.doi.org/10.1371/journal.pone.0075361

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