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Regression of Fibrosis and Reversal of Cirrhosis in Rats by Galectin Inhibitors in Thioacetamide-Induced Liver Disease
Galectin-3 protein is critical to the development of liver fibrosis because galectin-3 null mice have attenuated fibrosis after liver injury. Therefore, we examined the ability of novel complex carbohydrate galectin inhibitors to treat toxin-induced fibrosis and cirrhosis. Fibrosis was induced in ra...
Autores principales: | Traber, Peter G., Chou, Hsin, Zomer, Eliezer, Hong, Feng, Klyosov, Anatole, Fiel, Maria-Isabel, Friedman, Scott L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793988/ https://www.ncbi.nlm.nih.gov/pubmed/24130706 http://dx.doi.org/10.1371/journal.pone.0075361 |
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