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Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server

Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published...

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Detalles Bibliográficos
Autores principales: Jung, Sunghoon, Bae, Se-Eun, Ahn, Insung, Son, Hyeon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794089/
https://www.ncbi.nlm.nih.gov/pubmed/24124412
http://dx.doi.org/10.5808/GI.2013.11.3.155
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author Jung, Sunghoon
Bae, Se-Eun
Ahn, Insung
Son, Hyeon S.
author_facet Jung, Sunghoon
Bae, Se-Eun
Ahn, Insung
Son, Hyeon S.
author_sort Jung, Sunghoon
collection PubMed
description Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published. The reliability of the torsional system, which represents the native processes of structural change in the structural analysis, was partially proven with previous structural alignment studies. Here, a web server providing structural information and analysis based on the backbone torsional representation of a protein structure is newly introduced. The web server offers functions of secondary structure database search, secondary structure calculation, and pair-wise protein structure comparison, based on a backbone torsion angle representation system. Application of the implementation in pair-wise structural alignment showed highly accurate results. The information derived from this web server might be further utilized in the field of ab initio protein structure modeling or protein homology-related analyses.
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spelling pubmed-37940892013-10-11 Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server Jung, Sunghoon Bae, Se-Eun Ahn, Insung Son, Hyeon S. Genomics Inform Application Note Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published. The reliability of the torsional system, which represents the native processes of structural change in the structural analysis, was partially proven with previous structural alignment studies. Here, a web server providing structural information and analysis based on the backbone torsional representation of a protein structure is newly introduced. The web server offers functions of secondary structure database search, secondary structure calculation, and pair-wise protein structure comparison, based on a backbone torsion angle representation system. Application of the implementation in pair-wise structural alignment showed highly accurate results. The information derived from this web server might be further utilized in the field of ab initio protein structure modeling or protein homology-related analyses. Korea Genome Organization 2013-09 2013-09-30 /pmc/articles/PMC3794089/ /pubmed/24124412 http://dx.doi.org/10.5808/GI.2013.11.3.155 Text en Copyright © 2013 by the Korea Genome Organization http://creativecommons.org/licenses/by-nc/3.0/ It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/).
spellingShingle Application Note
Jung, Sunghoon
Bae, Se-Eun
Ahn, Insung
Son, Hyeon S.
Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
title Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
title_full Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
title_fullStr Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
title_full_unstemmed Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
title_short Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
title_sort protein backbone torsion angle-based structure comparison and secondary structure database web server
topic Application Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794089/
https://www.ncbi.nlm.nih.gov/pubmed/24124412
http://dx.doi.org/10.5808/GI.2013.11.3.155
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