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miRISC recruits decapping factors to miRNA targets to enhance their degradation

MicroRNA (miRNA)-induced silencing complexes (miRISCs) repress translation and promote degradation of miRNA targets. Target degradation occurs through the 5′-to-3′ messenger RNA (mRNA) decay pathway, wherein, after shortening of the mRNA poly(A) tail, the removal of the 5′ cap structure by decapping...

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Detalles Bibliográficos
Autores principales:	Nishihara, Tadashi, Zekri, Latifa, Braun, Joerg E., Izaurralde, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794582/ https://www.ncbi.nlm.nih.gov/pubmed/23863838 http://dx.doi.org/10.1093/nar/gkt619

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