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Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase

Uracil-DNA glycosylase (UDG) compromises the replication strategies of diverse viruses from unrelated lineages. Virally encoded proteins therefore exist to limit, inhibit or target UDG activity for proteolysis. Viral proteins targeting UDG, such as the bacteriophage proteins ugi, and p56, and the HI...

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Detalles Bibliográficos
Autores principales: Cole, Ambrose R., Ofer, Sapir, Ryzhenkova, Ksenia, Baltulionis, Gediminas, Hornyak, Peter, Savva, Renos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794593/
https://www.ncbi.nlm.nih.gov/pubmed/23892286
http://dx.doi.org/10.1093/nar/gkt633