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CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2

Androgen receptor (AR), a ligand-dependent transcription factor, plays a critical role in prostate cancer onset and progression, and its transcriptional function is mediated largely by distinct nuclear receptor co-regulators. Here, we show that cell cycle and apoptosis regulator 1 (CCAR1) functions...

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Detalles Bibliográficos
Autores principales: Seo, Woo-Young, Jeong, Byong Chang, Yu, Eun Ji, Kim, Hwa Jin, Kim, Seok-Hyung, Lim, Joung Eun, Kwon, Ghee Young, Lee, Hyun Moo, Kim, Jeong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794601/
https://www.ncbi.nlm.nih.gov/pubmed/23887938
http://dx.doi.org/10.1093/nar/gkt644