Cargando…

CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2

Androgen receptor (AR), a ligand-dependent transcription factor, plays a critical role in prostate cancer onset and progression, and its transcriptional function is mediated largely by distinct nuclear receptor co-regulators. Here, we show that cell cycle and apoptosis regulator 1 (CCAR1) functions...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seo, Woo-Young, Jeong, Byong Chang, Yu, Eun Ji, Kim, Hwa Jin, Kim, Seok-Hyung, Lim, Joung Eun, Kwon, Ghee Young, Lee, Hyun Moo, Kim, Jeong Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794601/ https://www.ncbi.nlm.nih.gov/pubmed/23887938 http://dx.doi.org/10.1093/nar/gkt644

Ejemplares similares

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation
por: Wang, Jun, et al.
Publicado: (2022)

HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers
por: Morozov, Viacheslav M, et al.
Publicado: (2023)

Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies
por: Chan, Siu Chiu, et al.
Publicado: (2015)

HDAC1 is required for GATA-1 transcription activity, global chromatin occupancy and hematopoiesis
por: Yan, Bowen, et al.
Publicado: (2021)

IKBKE activity enhances AR levels in advanced prostate cancer via modulation of the Hippo pathway
por: Bainbridge, Alex, et al.
Publicado: (2020)

Three-tiered role of the pioneer factor GATA2 in promoting androgen-dependent gene expression in prostate cancer
por: Wu, Dayong, et al.
Publicado: (2014)

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities
por: Kounatidou, Evangelia, et al.
Publicado: (2019)

Multidimensional profiling reveals GATA1-modulated stage-specific chromatin states and functional associations during human erythropoiesis
por: Li, Dong, et al.
Publicado: (2023)

IL-1β–specific recruitment of GCN5 histone acetyltransferase induces the release of PAF1 from chromatin for the de-repression of inflammatory response genes
por: Kim, Nari, et al.
Publicado: (2013)

CTCF-mediated chromatin looping provides a topological framework for the formation of phase-separated transcriptional condensates
por: Lee, Ryanggeun, et al.
Publicado: (2021)

Cyclin-dependent kinase 1 activity coordinates the chromatin associated state of Oct4 during cell cycle in embryonic stem cells
por: Kim, Hye Ji, et al.
Publicado: (2018)

Core promoter activity contributes to chromatin-based regulation of internal cryptic promoters
por: Lee, Bo Bae, et al.
Publicado: (2021)

Androgen receptor uses relaxed response element stringency for selective chromatin binding and transcriptional regulation in vivo
por: Sahu, Biswajyoti, et al.
Publicado: (2014)

The distinctive roles of erythroid specific activator GATA-1 and NF-E2 in transcription of the human fetal γ-globin genes
por: Woon Kim, Yea, et al.
Publicado: (2011)

Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy
por: Ji Yu, Eun, et al.
Publicado: (2011)

A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart
por: Iyer, Lavanya M, et al.
Publicado: (2018)

SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin
por: Toropainen, Sari, et al.
Publicado: (2015)

NuA3 HAT antagonizes the Rpd3S and Rpd3L HDACs to optimize mRNA and lncRNA expression dynamics
por: Kim, Ji Hyun, et al.
Publicado: (2020)

Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation
por: Bottardi, Stefania, et al.
Publicado: (2011)

Primary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1
por: Zhang, Ying, et al.
Publicado: (2009)

Differential coregulator requirements for function of the hematopoietic transcription factor GATA-1 at endogenous loci
por: Pope, Nathaniel J., et al.
Publicado: (2010)

Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells
por: Kang, Moo-Rim, et al.
Publicado: (2010)

Expression of stress-response ATF3 is mediated by Nrf2 in astrocytes
por: Kim, Kyu-Han, et al.
Publicado: (2010)

Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing
por: Choi, Jongkyu, et al.
Publicado: (2011)

Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation
por: Zhang, Yingchi, et al.
Publicado: (2017)

The novel GATA1-interacting protein HES6 is an essential transcriptional cofactor for human erythropoiesis
por: Wang, Zi, et al.
Publicado: (2023)

FOXO1 degradation via G9a-mediated methylation promotes cell proliferation in colon cancer
por: Chae, Yun-Cheol, et al.
Publicado: (2019)

SMAD3 promotes expression and activity of the androgen receptor in prostate cancer
por: Jeon, Hee-Young, et al.
Publicado: (2023)

Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance
por: Kim, Sung-Mi, et al.
Publicado: (2010)

DBC1 is a key positive regulator of enhancer epigenomic writers KMT2D and p300
por: Kim, Hwa Jin, et al.
Publicado: (2022)

Accessible gene borders establish a core structural unit for chromatin architecture in Arabidopsis
por: Lee, Hongwoo, et al.
Publicado: (2023)

Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions
por: Decker, Keith F., et al.
Publicado: (2012)

MicroRNA-26a induced by hypoxia targets HDAC6 in myogenic differentiation of embryonic stem cells
por: Lee, Sae-Won, et al.
Publicado: (2015)

The OTUD5–UBR5 complex regulates FACT-mediated transcription at damaged chromatin
por: de Vivo, Angelo, et al.
Publicado: (2019)

Chromatin condensation fluctuations rather than steady-state predict chromatin accessibility
por: Audugé, Nicolas, et al.
Publicado: (2019)

Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation
por: Duan, Lingling, et al.
Publicado: (2019)

BRG1 directly regulates nucleosome structure and chromatin looping of the α globin locus to activate transcription
por: Kim, Shin-Il, et al.
Publicado: (2009)

Lysine acetylation of the housekeeping sigma factor enhances the activity of the RNA polymerase holoenzyme
por: Kim, Ji-Eun, et al.
Publicado: (2020)

Establishment of active chromatin structure at enhancer elements by mixed-lineage leukemia 1 to initiate estrogen-dependent gene expression
por: Jeong, Kwang Won, et al.
Publicado: (2014)

CDK2-dependent phosphorylation of Suv39H1 is involved in control of heterochromatin replication during cell cycle progression
por: Park, Su Hyung, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3tjlv23h25n3pmrvqsq3g4o6lf