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Frataxin mRNA Isoforms in FRDA Patients and Normal Subjects: Effect of Tocotrienol Supplementation

Friedreich's ataxia (FRDA) is caused by deficient expression of the mitochondrial protein frataxin involved in the formation of iron-sulphur complexes and by consequent oxidative stress. We analysed low-dose tocotrienol supplementation effects on the expression of the three splice variant isofo...

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Detalles Bibliográficos
Autores principales: Abruzzo, Provvidenza Maria, Marini, Marina, Bolotta, Alessandra, Malisardi, Gemma, Manfredini, Stefano, Ghezzo, Alessandro, Pini, Antonella, Tasco, Gianluca, Casadio, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794619/
https://www.ncbi.nlm.nih.gov/pubmed/24175286
http://dx.doi.org/10.1155/2013/276808