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Trifluoroethanol Modulates Amyloid Formation by the All α-Helical URN1 FF Domain
Amyloid fibril formation is implicated in different human diseases. The transition between native α-helices and nonnative intermolecular β-sheets has been suggested to be a trigger of fibrillation in different conformational diseases. The FF domain of the URN1 splicing factor (URN1-FF) is a small al...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794755/ https://www.ncbi.nlm.nih.gov/pubmed/23999589 http://dx.doi.org/10.3390/ijms140917830 |