Liberation of GPI-Anchored Prion from Phospholipids Accelerates Amyloidogenic Conversion

Prion diseases or transmissible spongiform encephalopathies are a rare group of fatal neurodegenerative illnesses in humans and animals caused by misfolding of prion protein (PrP). Prion protein is a cell-surface glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed mostly in the centra...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Shen-Jie, Yu, Kun-Hua, Wu, Jhih-Ru, Lee, Chin-Fa, Jheng, Cheng-Ping, Chen, Hau-Ren, Lee, Cheng-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794761/
https://www.ncbi.nlm.nih.gov/pubmed/24005859
http://dx.doi.org/10.3390/ijms140917943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794761/
https://www.ncbi.nlm.nih.gov/pubmed/24005859
http://dx.doi.org/10.3390/ijms140917943

Ejemplares similares