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Liberation of GPI-Anchored Prion from Phospholipids Accelerates Amyloidogenic Conversion

Prion diseases or transmissible spongiform encephalopathies are a rare group of fatal neurodegenerative illnesses in humans and animals caused by misfolding of prion protein (PrP). Prion protein is a cell-surface glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed mostly in the centra...

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Detalles Bibliográficos
Autores principales:	Lin, Shen-Jie, Yu, Kun-Hua, Wu, Jhih-Ru, Lee, Chin-Fa, Jheng, Cheng-Ping, Chen, Hau-Ren, Lee, Cheng-I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794761/ https://www.ncbi.nlm.nih.gov/pubmed/24005859 http://dx.doi.org/10.3390/ijms140917943

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